| Ultrasound detection of Down syndrome: is it really possible? | |
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MedLine Citation:
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PMID: 2521379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Several ultrasonographic signs have been described in second-trimester fetuses at high risk for Down syndrome. We examined these parameters in twin pregnancies in which one fetus was affected with Down syndrome and the other was normal. Biparietal diameter to femur length ratio was concordant (either normal or abnormal) in eight of nine sets of twins. Actual femur length to expected femur length ratio was concordant in seven of nine sets of twins. Nuchal fold thickening (6 mm or more) correctly identified five out of nine affected fetuses and was not present in any of the normal fetuses. In conclusion, neither ratio was helpful in differentiating the fetus with Down syndrome from its normal cotwin. A thickened nuchal fold was the most informative parameter examined. |
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Authors:
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L Lynch; G S Berkowitz; U Chitkara; I A Wilkins; K E Mehalek; R L Berkowitz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 73 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1989 Feb |
Date Detail:
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Created Date: 1989-02-23 Completed Date: 1989-02-23 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 267-70 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics, Mount Sinai Medical Center, New York, New York. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Diseases in Twins* Down Syndrome / diagnosis* Female Fetal Diseases / diagnosis* Fetus / anatomy & histology Humans Pregnancy Pregnancy, Multiple* Prenatal Diagnosis* Risk Factors Ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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