Document Detail

Ultrasound-detected hepatic periportal thickening in patients with prolonged pyrexia.
MedLine Citation:
PMID:  9684626     Owner:  NLM     Status:  MEDLINE    
Hepatic periportal thickening (HPT) detected by ultrasonography has been established as a reliable tool for measuring hepatic morbidity due to schistosomiasis. During ultrasonographic examination of patients with prolonged pyrexia, we frequently noticed minimal grades of HPT in patients without a history of schistosomiasis. This led to ultrasonographic studies of conditions other than schistosomiasis in which HPT may occur. Subjects included 460 patients with Schistosoma haematobium infection, 107 urban patients with prolonged pyrexia without previous exposure to schistosomiasis, and 288 healthy controls unexposed to schistosomiasis. Grade I HPT was more prevalent (P < 0.001) in patients with pyrexia (56.1%) than in those with S. haematobium (32.2%) and was more frequent (P < 0.001) in patients with S. haematobium than in controls (11.1%). Typhoid fever was the most common febrile illness causing HPT. Grade II lesions were rare in patients with pyrexia (2.8%) or schistosomiasis (0.9%). Grade III lesions were present in only one patient with S. haematobium. Mild grades of HPT can occur in infectious diseases other than schistosomiasis. Cellular infiltration in the portal tract from chronic infectious diseases can frequently give the ultrasonographic appearance of grade I HPT.
A Medhat; M Nafeh; Y Swifee; A Helmy; S Zaki; M Shehata; S Ibrahim; D A Abdel-Kader; G T Strickland
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  59     ISSN:  0002-9637     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-08-04     Completed Date:  1998-08-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  45-8     Citation Subset:  AIM; IM    
Department of Tropical Medicine, Assiut University Faculty of Medicine, Egypt.
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MeSH Terms
Age Factors
Brucellosis / complications
Fever / complications*,  etiology,  ultrasonography
Hematologic Neoplasms / complications
Hepatitis, Viral, Human / complications
Hepatomegaly / etiology,  ultrasonography
Immune System Diseases / complications
Liver / ultrasonography*
Schistosomiasis haematobia / complications*,  ultrasonography
Sex Factors
Spleen / ultrasonography
Splenomegaly / etiology,  ultrasonography
Time Factors
Typhoid Fever / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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