Document Detail


Ultrasound cervical measurement and prediction of spontaneous preterm birth in ICSI pregnancies: a prospective controlled study.
MedLine Citation:
PMID:  19192354     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective controlled study was performed in which transvaginal ultrasound measurement of cervical length was compared in 222 twin ICSI pregnancies, 122 singleton ICSI pregnancies and 51 spontaneous singleton pregnancies. Preterm birth was defined as <or=34 weeks. Full data were obtained for 193 twin pregnancies (group A), 102 singleton pregnancies (group B) and 51 spontaneous singleton pregnancies (group C). Cervical length at midterm was not statistically different between the three groups: group A, 37.6 +/- 7.1 mm; group B, 37.2 +/- 7.2 mm; and group C, 39.2 +/- 5.4 mm. The incidence of preterm birth was statistically different between groups: 30.5% in group A; 17.6% in group B; and 3.9% in group C (P = 0.011). The ROC curve for optimum cut-off of cervical length in prediction of preterm birth for group A was 38.05 mm, sensitivity 67%, specificity 50%, positive predictive value (PPV) 37.7, and negative predictive value (NPV) 78.1. For group B the data were 33.05 mm, sensitivity 50%, specificity 70%, PPV 34.6, and NPV 88.1. Contrary to the situation for spontaneous pregnancies, midtrimester cervical length measurement in ICSI singleton and twin pregnancies is not a predictor for preterm birth.
Authors:
Mona M Aboulghar; Mohamed A Aboulghar; Latouna Mourad; Gamal I Serour; Ragaa T Mansour
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  18     ISSN:  1472-6491     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-04     Completed Date:  2009-05-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  296-300     Citation Subset:  IM    
Affiliation:
The Egyptian IVF-ET Centre, No.3, St 181, Hadaek El Maadi, Maadi, Cairo, Egypt. monaaboulghar71@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Case-Control Studies
Cervical Length Measurement* / methods
Female
Follow-Up Studies
Humans
Predictive Value of Tests
Pregnancy
Pregnancy Trimester, Second / physiology
Pregnancy, Multiple / physiology
Premature Birth / diagnosis*
Prospective Studies
ROC Curve
Sperm Injections, Intracytoplasmic*
Twins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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