Document Detail


Ultrasound-assisted emulsification microextraction coupled with gas chromatography-mass spectrometry using the Taguchi design method for bisphenol migration studies from thermal printer paper, toys and baby utensils.
MedLine Citation:
PMID:  22526639     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The optimization of a clean procedure based on ultrasound-assisted emulsification liquid-liquid microextraction for the sensitive determination of four bisphenols is presented. The miniaturized technique was coupled with gas chromatography-mass spectrometry after derivatization by in situ acetylation. The Taguchi experimental method, an orthogonal array design, was applied to find the optimal combination of seven factors (each factor at three levels) influencing the emulsification, extraction and collection efficiency, namely acetic anhydride volume, sodium phosphate concentration, carbon tetrachloride volume, aqueous sample volume, sodium chloride concentration and ultrasound power and application time. A second factorial design was applied with four factors and five levels for each factor, 25 experiments being performed in this instance. The matrix effect was evaluated, and it was concluded that sample quantification can be done by calibration with aqueous standards. The detection limits ranged from 0.01 to 0.03 ng mL(-1) depending on the compound. The environmentally friendly sample pretreatment procedure was applied to study the migration of the bisphenols from different types of samples: thermal printer paper, compact discs, digital versatile discs, small tight-fitting waistcoats, baby's bottles, baby bottle nipples of different materials and children's toys.
Authors:
Pilar Viñas; Ignacio López-García; Natalia Campillo; Ricardo E Rivas; Manuel Hernández-Córdoba
Related Documents :
11126129 - Laboratory database to manage electrophoresis and chromatography separations and the as...
1752389 - A new method of separation and quantitation of mucus glycoprotein in rat gastric mucus ...
1696829 - Isolation and characterization of human fibroblast tenascin. an extracellular matrix gl...
5166859 - Purification and characterization of the l component of streptococcus zymogenes lysin.
21665569 - Detection of vibrio parahaemolyticus in mediterranean mussels (mytilus galloprovinciali...
15690429 - A highly sensitive method for quantification of myosin light chain phosphorylation by c...
3372619 - Identification and quantitation of trenbolone in bovine tissue by gas chromatography-ma...
23605709 - Detection of unknown toxic mycotoxins inaspergillus nidulans using a structure-activity...
22849359 - A new approach to determining pharmacologic adulteration of herbal weight loss products.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-13
Journal Detail:
Title:  Analytical and bioanalytical chemistry     Volume:  -     ISSN:  1618-2650     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134327     Medline TA:  Anal Bioanal Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Rapid identification, by use of the LTQ Orbitrap hybrid FT mass spectrometer, of antifungal compound...
Next Document:  Selective detection of alkaloids in MALDI-TOF: the introduction of a novel matrix molecule.