Document Detail

Ultrasound assessment of the polycystic ovary: international consensus definitions.
MedLine Citation:
PMID:  14714587     Owner:  NLM     Status:  MEDLINE    
The polycystic ovary syndrome (PCOS) is a heterogeneous condition, the pathophysiology of which appears to be both multifactorial and polygenic. The definition of the syndrome has been much debated. Key features include menstrual cycle disturbance, hyperandrogenism and obesity. There are many extra-ovarian aspects to the pathophysiology of PCOS, yet ovarian dysfunction is central. At a recent joint ASRM/ESHRE consensus meeting, a refined definition of the PCOS was agreed, encompassing a description of the morphology of the polycystic ovary (PCO). According to the available literature, the criteria fulfilling sufficient specificity and sensitivity to define the PCO should have at least one of the following: either 12 or more follicles measuring 2-9 mm in diameter, or increased ovarian volume (> 10 cm3). If there is a follicle > 10 mm in diameter, the scan should be repeated at a time of ovarian quiescence in order to calculate volume and area. The presence of a single PCO is sufficient to provide the diagnosis. The distribution of follicles and a description of the stroma are not required in the diagnosis. Increased stromal echogenicity and/or stromal volume are specific to PCO, but it has been shown that the measurement of ovarian volume (or area) is a good surrogate for quantification of the stroma in clinical practice. A woman having PCO in the absence of an ovulation disorder or hyperandrogenism ('asymptomatic PCO') should not be considered as having PCOS, until more is known about this situation. Three-dimensional and Doppler ultrasound studies may be useful research tools but are not required in the definition of PCO. This review outlines evidence for the current ultrasound definition of the polycystic ovary and technical specifications.
Adam H Balen; Joop S E Laven; Seang-Lin Tan; Didier Dewailly
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Publication Detail:
Type:  Consensus Development Conference; Journal Article; Review    
Journal Detail:
Title:  Human reproduction update     Volume:  9     ISSN:  1355-4786     ISO Abbreviation:  Hum. Reprod. Update     Publication Date:    2003 Nov-Dec
Date Detail:
Created Date:  2004-01-12     Completed Date:  2004-07-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9507614     Medline TA:  Hum Reprod Update     Country:  England    
Other Details:
Languages:  eng     Pagination:  505-14     Citation Subset:  IM    
Department of Reproductive Medicine, Leeds General Infirmary, Leeds, UK.
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MeSH Terms
Imaging, Three-Dimensional
Polycystic Ovary Syndrome / ultrasonography*
Terminology as Topic*
Ultrasonography, Doppler

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