Document Detail


Ultrasound angioplasty: an update review.
MedLine Citation:
PMID:  12623409     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The use of therapeutic ultrasound to treat atherosclerosis and thrombosis has been appreciated for decades. However, it was only the explosive growth of angioplasty in the 1980s that brought real momentum to the development of therapeutic catheter ultrasound. The idea behind this technique was that ultrasound, by its bioselectivity, might provide a solution to some of the shortcomings of balloon angioplasty. In the late 1980s, two groups, headed by Rosenschein and Siegel, began serious work to address the technical challenge of developing a catheter that would provide efficient external ultrasound energy to the lesion. Current catheters from both groups consist of a solid metal probe which is connected to a piezoelectric transducer. In the distal segment, the wire is specially designed to increase energy delivery. Initial in vitro studies concentrated on understanding the mechanisms of ablation and the effects of mechanical vibration, thermal phenomena and cavitation. Clinical studies of ultrasound ablation were initially performed in peripheral vessels. Later, after safety had been assured, clinical studies involving the coronary arteries began to take place. In this article we aim to update the reader about the experimental and limited clinical experience in this novel technique for treating different kinds of arterial obstruction.
Authors:
David Brosh; Hylton I Miller; Itzhak Herz; Shlomo Laniado; Uri Rosenschein
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  International journal of cardiovascular interventions     Volume:  1     ISSN:  1462-8848     ISO Abbreviation:  Int J Cardiovasc Intervent     Publication Date:  1998  
Date Detail:
Created Date:  2003-Mar-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815622     Medline TA:  Int J Cardiovasc Intervent     Country:  -    
Other Details:
Languages:  ENG     Pagination:  11-18     Citation Subset:  -    
Affiliation:
The Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
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