Document Detail

Ultrasound predictors of mortality in monochorionic twins with selective intrauterine growth restriction.
MedLine Citation:
PMID:  20878679     Owner:  NLM     Status:  In-Process    
OBJECTIVES: The aim of this study was to evaluate the use of ultrasound assessment to predict risk of mortality in expectantly managed monochorionic twin fetuses with selective intrauterine growth restriction (sIUGR).
METHODS: This was a retrospective study of 101 monochorionic twin pregnancies diagnosed with sIUGR before 26 weeks of gestation. All patients were under expectant management during the observation period. At the initial evaluation, the presence or absence of each of the following abnormalities was documented: oligohydramnios; stuck twin phenomenon; severe IUGR < 3(rd) centile of estimated fetal weight; abnormal Doppler in the umbilical artery; and polyhydramnios in the larger twin. The relationships between these ultrasound findings and mortality of sIUGR fetuses were evaluated using multiple logistic regression analysis.
RESULTS: Of 101 sIUGR twins, 22 (21.8%) fetuses suffered intrauterine demise and nine (8.9%) suffered neonatal death; 70 (69.3%) survived the neonatal period. Multiple logistic regression analysis revealed that the stuck twin phenomenon (odds ratio (OR): 14.5; 95% CI: 2.2-93.2; P = 0.006) and constantly absent diastolic flow in the umbilical artery (OR: 29.4; 95% CI: 3.3-264.0; P = 0.003) were significant risk factors for mortality.
CONCLUSIONS: Not only abnormal Doppler flow in the umbilical artery but also severe oligohydramnios should be recognized as important indicators for mortality in monochorionic twins with sIUGR.
K Ishii; T Murakoshi; S Hayashi; M Saito; H Sago; Y Takahashi; M Sumie; M Nakata; M Matsushita; T Shinno; H Naruse; Y Torii
Related Documents :
3688079 - The length of the human umbilical cord in twin pregnancies.
6536139 - Coitus-induced ovulation and its implications for estimates of some reproductive parame...
20677479 - Why the twinning rate is higher in africa than elsewhere: an analysis of selected factors.
2130829 - Fetal urine production in normal twins and in twins with acute polyhydramnios.
15607019 - Twin paternity.
18935999 - Successful treatment of twin-twin transfusion syndrome by occlusion of placental vessel...
15459939 - Development of the human fetal pons: in utero ultrasonographic study.
18393379 - First-trimester diagnosis of cesarean scar ectopic pregnancy.
22853319 - The impact of african ethnicity and migration on pregnancy in women living with hiv in ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  37     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  22-6     Citation Subset:  IM    
Division of Perinatology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A reassessment of biochemical marker distributions in trisomy 21-affected and unaffected twin pregna...
Next Document:  Tetrad selectivity in polarity-driven switch peptides: the best turn is not always the best nucleati...