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Ultrasonography-guided percutaneous thrombin injection of postcatheterization pseudoaneurysms.
MedLine Citation:
PMID:  22198911     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: This study retrospectively evaluated ultrasonography-guided (US-guided) percutaneous thrombin injection for the treatment of postcatheterization femoral and brachial artery pseudoaneurysms. MATERIALS AND METHODS: Fifty-five patients with postcatheterization femoral artery (n=53) or brachial artery (n=2) pseudoaneurysms were treated using US-guided human thrombin (500 IU/mL) injection. Pseudoaneurysm size, thrombin dose, therapy outcome, and complications were documented. Follow-up color Doppler US was performed 7 and 30 days after treatment. Short-duration supplemental compression was applied to six patients at the first week follow-up examination after a reinjection of thrombin had failed. RESULTS: Mean pseudoaneurysm volume was 20.3±18.7 cm3. The mean injected thrombin dose was 478±238 IU. Thirty-eight (69.1%) of the 55 pseudoaneurysms were thrombosed with a single injection, and 11 of 17 pseudoaneurysms were thrombosed after a second injection. All (100%) of the 41 pseudoaneurysms that were diagnosed within the first two weeks of postcatheterization were successfully treated. The overall primary success rate was 89.1% (49 of 55 pseudoaneurysms). Supplemental compression promoted thrombosis in four of the six patients who had treatment failure with thrombin injection. The secondary success rate was 96.4% (53 of 55 pseudoaneurysms). There were no complications. CONCLUSION: US-guided thrombin injection was most successful within the first two weeks, and the supplemental compression might aid in the closure of partially thrombosed pseudoaneurysms.
Authors:
Kamil Gurel; Serkan Gur; Ugur Ozkan; Guven Tekbas; Hakan Onder; Levent Oğuzkurt
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-23
Journal Detail:
Title:  Diagnostic and interventional radiology (Ankara, Turkey)     Volume:  -     ISSN:  1305-3612     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101241152     Medline TA:  Diagn Interv Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Radiology, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
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