Document Detail


Ultrasonography of the brain in preterm infants and its correlation with neurodevelopmental outcome.
MedLine Citation:
PMID:  8617548     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two hundred and eighteen preterm neonates had ultrasonography (USG) brain done on third, and/or seventh and fourteenth day of life. Fifty eight (26.3%) had intraventricular/ periventricular hemorrhage, 3 had parenchymal lesions. 46 had Grade I hemorrhage, 9 had Grade II, 2 had Grade III and 1 had Grade IV hemorrhage. Grade III and IV hemorrhages occurred in neonates below 34 weeks gestation. There was an inverse relationship between gestation age and hemorrhage (p = 0.0001). A comparison of incidence of hemorrhage between preterms who were appropriate for gestational age was not significant. Out of the 63 neonates who had serial USGs on the third and seventh day of life, 15 of the 16 bleeds (94%) were detected on the third day itself, indicating it to be a opportune time for doing an USG. USG at term (40 weeks postconceptual age) was done in 99 infants to see if it could correctly predict the neurodevelopmental outcome using the Bayley Scales of Infant Development. Out of these 99 infants, 72 came for the developmental assessment at one year. One neonate who had periventricular leucomalacia with cystic changes on USG at term, was grossly abnormal with cerebral palsy and mental retardation. Six infants showed delayed development with a mean mental development quotient of 79.1 +/- 1.72 at 2 years. The specificity of USG at term for predicting outcome was 89.2% and negative predictive outcome was 90%, indicating that a normal USG at term predicted a good neurodevelopmental outcome.
Authors:
S Chaudhari; A S Kinare; R Kumar; A N Pandit; M Deshpande
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian pediatrics     Volume:  32     ISSN:  0019-6061     ISO Abbreviation:  Indian Pediatr     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1996-06-07     Completed Date:  1996-06-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  735-42     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, K.E.M. Hospital, Pune.
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MeSH Terms
Descriptor/Qualifier:
Cerebral Hemorrhage / classification,  complications*,  ultrasonography
Developmental Disabilities / epidemiology*,  etiology
Echoencephalography*
Follow-Up Studies
Humans
India / epidemiology
Infant, Newborn
Infant, Premature*
Prognosis

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