Document Detail

Ultrasonographic left cardiac axis deviation: a marker for fetal anomalies.
MedLine Citation:
PMID:  7824228     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine if a relation exists between left cardiac axis deviation and fetal anomalies. METHODS: Estimation of cardiac axis was attempted prospectively as part of the cardiac examination in approximately 41,500 second- and third-trimester fetuses scanned between 1987-1993. Those with heart axes greater than 75 degrees to the left were considered to have left axis deviation. Only cases with postnatal follow-up were included. RESULTS: Thirty-four fetuses with left cardiac axis deviation had postnatal follow-up; eight were normal and 26 abnormal (positive predictive value 76%). Twenty-one fetuses had cardiac abnormalities (ten of these had additional extracardiac findings), and five had extracardiac findings only. CONCLUSION: Although left cardiac axis deviation can occur as an isolated sonographic finding in an otherwise normal fetus, most cases will demonstrate abnormalities of cardiac and/or extracardiac anatomy. Left cardiac axis deviation is largely associated with cardiac abnormalities, especially conotruncal anomalies, which may not be detectable by a four-chamber view alone. Therefore, the cardiac axis should be examined routinely as part of the four-chamber view of the fetal heart.
R S Smith; C H Comstock; J S Kirk; W Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  85     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-02-14     Completed Date:  1995-02-14     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  187-91     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, William Beaumont Hospital, Royal Oak, Michigan.
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MeSH Terms
Congenital Abnormalities / ultrasonography
Fetal Diseases / ultrasonography
Fetal Heart / ultrasonography*
Heart Defects, Congenital / ultrasonography*
Predictive Value of Tests
Risk Factors
Ultrasonography, Prenatal*

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