| Ultrasonographic detection of thyroid nodules in hemodialysis patients in Japan. | |
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MedLine Citation:
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PMID: 20609186 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The study of thyroid nodules in hemodialyzed patients using ultrasonography has been described in a limited number of reports. The thyroid glands of 143 patients with end-stage renal disease on hemodialysis were examined by ultrasonography using frequency probes. Although a goiter (thyroid volume > 20 mL) was observed in only 20 patients (14%), nodular lesions of the thyroid gland were more frequent and found in 85 patients (59.4%), especially in female patients (42 patients, 72.4%). The etiology of thyroid nodular lesions was as follows: cyst in 43 (30.0%), adenomatous goiter in 14 (9.8%), adenoma in 11 (7.7%), hypoechoic lesion in 17 (11.9%), and intrathyroid calcification in 8 (5.6%). Ultrasound-guided fine-needle aspiration cytology was performed in 5 patients, but no abnormal cells were found. Compared to patients without nodules, the age was higher in patients with cysts (54 +/- 15 vs. 63 +/- 13 years; P < 0.05) and hypoechoic lesions (70 +/- 13 years; P < 0.05). The serum thyroglobulin level was higher in patients with adenomatous goiters (26 +/- 28 vs. 148 +/- 166 ng/mL; P < 0.05). The thyroid volume was greater in patients with adenomatous goiters (14.2 +/- 5.7 vs. 19.0 +/- 7.3 mL; P < 0.05) and adenomas (18.2 +/- 6.7 mL; P < 0.05). In conclusion, patients undergoing hemodialysis frequently develop thyroid abnormalities and ultrasonography is a useful imaging modality to identify these lesions. |
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Authors:
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Toru Sanai; Ken Okamura; Teruo Inoue; Tetsuya Abe; Kazuhiko Tsuruya; Koichi Node |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Volume: 14 ISSN: 1744-9987 ISO Abbreviation: Ther Apher Dial Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2010-10-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101181252 Medline TA: Ther Apher Dial Country: Australia |
Other Details:
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Languages: eng Pagination: 323-7 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular and Renal Medicine, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan. sunny@cc.saga-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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pathology Adult Age Factors Aged Aged, 80 and over Biopsy, Needle / methods Female Goiter / etiology, pathology, ultrasonography Humans Japan Kidney Failure, Chronic / complications, therapy* Male Middle Aged Renal Dialysis* Sex Factors Thyroglobulin / blood Thyroid Nodule / etiology, ultrasonography* |
| Chemical | |
Reg. No./Substance:
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9010-34-8/Thyroglobulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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