Document Detail

Ultrasonographic and FDG-PET imaging in active giant cell arteritis of the carotid arteries.
MedLine Citation:
PMID:  16363284     Owner:  NLM     Status:  MEDLINE    
Inflammation of the arterial wall has been demonstrated by 18 Fluoro-Deoxyglucose PET imaging in patients with Takayasu's and temporal arteritis. We used ultrasonography and FDG-PET for structural and metabolic imaging of the carotid artery to diagnose giant cell arteritis without biopsy. In a 72 years old patient with isolated clinical and paraclinical signs of severe systemic inflammation ultrasonogaphy showed concentric hypoechogenic mural thickening of the carotidarteries and high FDG uptake in the left carotid, both axillary and subclavian arteries and the aorta. Clinical and paraclinical abnormalities showed a typical response to steroid treatment. In conclusion a combined approach using ultrasound and FDG-PET seems to be helpful in the diagnosis of GCA of large arteries particularly in patients with atypical manifestations of the disease and negative or unavailable biopsy of the temporal artery.
K Pfadenhauer; T Rüll
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  VASA. Zeitschrift für Gefässkrankheiten     Volume:  34     ISSN:  0301-1526     ISO Abbreviation:  VASA     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-12-20     Completed Date:  2006-01-20     Revised Date:  2012-10-19    
Medline Journal Info:
Nlm Unique ID:  0317051     Medline TA:  Vasa     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  269-71     Citation Subset:  IM    
Departments of Neurology and Clinical Neurophysiology, Augsburg, Germany.
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MeSH Terms
Carotid Arteries / radionuclide imaging*,  ultrasonography*
Fluorodeoxyglucose F18 / diagnostic use*
Giant Cell Arteritis / radionuclide imaging*,  ultrasonography*
Image Enhancement / methods*
Positron-Emission Tomography / methods
Radiopharmaceuticals / diagnostic use*
Subtraction Technique
Ultrasonography / methods
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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