| Ultrasonically mediated solute permeation through polymer barriers. | |
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MedLine Citation:
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PMID: 2880958 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of ultrasound on the permeation of benzoic acid through polydimethylsiloxane, and hydrocortisone through cellulose was investigated. Ultrasonic irradiation resulted in a 23% increase in the permeability coefficient of hydrocortisone in a cellulose film. A 14% increase in permeability coefficient was observed for benzoic acid in a polydimethylsiloxane film. The effects of ultrasound on stagnant aqueous diffusion layers, membrane-solution interfacial temperature, membrane integrity, and diffusant stability were investigated. These factors were not responsible for the observed increases in permeability. |
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Authors:
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T N Julian; G M Zentner |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of pharmacy and pharmacology Volume: 38 ISSN: 0022-3573 ISO Abbreviation: J. Pharm. Pharmacol. Publication Date: 1986 Dec |
Date Detail:
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Created Date: 1987-04-01 Completed Date: 1987-04-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376363 Medline TA: J Pharm Pharmacol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 871-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Benzoates
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analysis Benzoic Acid Cellulose Diffusion Dimethylpolysiloxanes / analysis Hydrocortisone / analysis Membranes, Artificial Permeability* Polymers* Solubility Spectrophotometry, Ultraviolet Temperature Ultrasonics* |
| Chemical | |
Reg. No./Substance:
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0/Benzoates; 0/Dimethylpolysiloxanes; 0/Membranes, Artificial; 0/Polymers; 50-23-7/Hydrocortisone; 65-85-0/Benzoic Acid; 9004-34-6/Cellulose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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