Document Detail

Ultrasonically guided fine-needle alcohol injection as an adjunct to medical treatment in secondary hyperparathyroidism.
MedLine Citation:
PMID:  3991588     Owner:  NLM     Status:  MEDLINE    
In 12 uraemic patients with symptomatic secondary hyperparathyroidism, 13 parathyroid hyperplasias, detected by sonography and confirmed by fine-needle aspiration biopsy, were treated by ultrasonically-guided percutaneous injection of absolute ethanol, in order to reduce the gland mass. Only in the larger glands were significant volume reductions recorded, whereas in the smaller ones evident structural changes were observed. In most cases with single lesions, a reduced incidence of vitamin D hypercalcaemia and a permanent improvement in bone alkaline phosphatase and PTH were documented. This technique can be usefully employed either as an alternative to surgery in selected cases, or as support to medical therapy in single lesions.
A Giangrande; P Cantù; L Solbiati; C Ravetto
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress     Volume:  21     ISSN:  0308-9401     ISO Abbreviation:  Proc Eur Dial Transplant Assoc Eur Ren Assoc     Publication Date:  1985  
Date Detail:
Created Date:  1985-06-19     Completed Date:  1985-06-19     Revised Date:  2008-02-26    
Medline Journal Info:
Nlm Unique ID:  8503947     Medline TA:  Proc Eur Dial Transplant Assoc Eur Ren Assoc     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  895-901     Citation Subset:  IM    
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MeSH Terms
Ethanol / administration & dosage*
Hyperparathyroidism, Secondary / drug therapy*,  etiology
Uremia / complications
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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