Document Detail


Ultrasonic viscoelasticity imaging of nonpalpable breast lesions.
MedLine Citation:
PMID:  19963829     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prognosis of breast cancer patients improves with early and accurate diagnosis. A small clinical study was conducted with 21 women having a single nonpalpable breast lesion, each detected mammographically with later pathology confirmation. Elasticity images were acquired on each patient to test for the ability to differentiating malignant and benign lesions. The mechanical relaxation time T(1) images showed a tissue-specific T(1) contrast that is negative for all 11 malignant lesions and positive for all 10 benign lesions. Strain images were estimated using a regularized multi-scale optical flow (ROF) algorithm. Adjustments to the input parameters to the ROF and their subsequent effects on T(1) estimation and computation time are shown to have a strong effect of diagnostic performance.
Authors:
Yupeng Qiu; Michael F Insana
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2009     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-07     Completed Date:  2010-04-08     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4424-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Algorithms
Breast Neoplasms / ultrasonography*
Elasticity Imaging Techniques / methods*
Female
Humans
Middle Aged
Phantoms, Imaging
Viscosity
Grant Support
ID/Acronym/Agency:
CA082497/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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