Document Detail

Ultrasonic tissue characterization in predicting residual ischemia and myocardial viability for patients with acute myocardial infarction.
MedLine Citation:
PMID:  9833578     Owner:  NLM     Status:  MEDLINE    
The identification of viable myocardium and residual ischemia in patients with acute myocardial infarction has important prognostic implications. The ultrasonic tissue characterization with integrated backscatter and dobutamine-atropine stress echocardiography were performed 8.3+/-3 days after AMI in 30 patients. After coronary angioplasty for the residual stenosis of infarct-related artery, both modalities were repeated. The parameter obtained from ultrasonic tissue characterization, phase-weighted variation, could differentiate the myocardium with residual coronary stenosis or nonviable myocardium from the viable myocardium without residual coronary stenosis (p < 0.001). Using the cutoff value of 5.8 dB, the sensitivity, specificity and accuracy for detecting viable myocardium without residual coronary stenosis were 75%, 100% and 90.2%, respectively. The phase-weighted variation of the viable infarction zone restored after the coronary stenosis was relieved. In contrast, the nonviable myocardium had a small phase-weighted variation that was irrelevant to the patency of the infarct-related artery. The ultrasonic tissue characterization may be used in identifying patients with acute myocardial infarction whose infarction zones are viable without residual ischemia.
L C Lin; C C Wu; Y L Ho; M F Chen; C S Liau; Y T Lee
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  24     ISSN:  0301-5629     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1999-01-28     Completed Date:  1999-01-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1107-20     Citation Subset:  IM    
Department of Internal Medicine (Cardiology Section), National Taiwan University Hospital, Taipei.
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MeSH Terms
Atropine / diagnostic use
Coronary Angiography
Coronary Disease / therapy
Dobutamine / diagnostic use
Exercise Test
Follow-Up Studies
Heart Ventricles / physiopathology,  ultrasonography*
Middle Aged
Myocardial Contraction
Myocardial Infarction / physiopathology,  therapy,  ultrasonography*
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity
Thrombolytic Therapy
Reg. No./Substance:
34368-04-2/Dobutamine; 51-55-8/Atropine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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