Document Detail

Ultrasonic resection of neuroblastomas. Long-term local tumor control.
MedLine Citation:
PMID:  7632154     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the effectiveness of ultrasonic aspiration in achieving local tumor control of bulky neutroblastomas that are considered unresectable by conventional means. DESIGN: A retrospective review of 12 patients undergoing ultrasonic aspiration as part of multimodal treatment protocols. SETTING: A pediatric oncology referral center. PATIENTS: Twelve children with large neuroblastomas located in the abdomen (n = 5), chest (n = 5), and neck (n = 2). Follow-up was 1.5 to 7.5 years. INTERVENTIONS: Ultrasonic aspiration of the tumor was primary therapy (n = 7) or followed initial chemotherapy (n = 5). All patients underwent subsequent chemotherapy or autologous bone marrow transplantation. MAIN OUTCOME MEASURES: The incidences of residual disease and local recurrence were examined. RESULTS: Tumor-related symptoms were effectively relieved in all 12 patients. Recurrent local disease led to death in two. One patient died of distant metastases. CONCLUSIONS: Ultrasonic aspiration minimized blood loss and did not cause damage to adjacent organs. It provided nearly complete tumor resection, enhanced the effectiveness of chemotherapy protocols, and decreased the need for supportive care. Ultrasonic aspiration is a safe and effective method for obtaining local control of large neuroblastomas.
H Applebaum; L E Feinfeld
Related Documents :
7632154 - Ultrasonic resection of neuroblastomas. long-term local tumor control.
15933424 - Metastatic adrenal neuroblastoma in an adult.
16418884 - The influence of biologic factors on the surgical decision in advanced neuroblastoma.
21422314 - Diagnosis-to-treatment interval and control of locoregionally advanced head and neck ca...
24438614 - Efficacy and safety of icotinib in chinese patients with advanced non-small cell lung c...
16456814 - Second autologous or allogeneic transplantation after the failure of first autograft in...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of surgery (Chicago, Ill. : 1960)     Volume:  130     ISSN:  0004-0010     ISO Abbreviation:  Arch Surg     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-09-07     Completed Date:  1995-09-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9716528     Medline TA:  Arch Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  905-8     Citation Subset:  AIM; IM    
Division of Pediatric Surgery, Kaiser Permanente Medical Center, Los Angeles, Calif., USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Abdominal Neoplasms / therapy*
Child, Preschool
Follow-Up Studies
Head and Neck Neoplasms / therapy*
Infant, Newborn
Neoplasm Recurrence, Local / therapy*
Neoplasm, Residual
Neuroblastoma / therapy*
Retrospective Studies
Suction / methods*
Treatment Outcome
Ultrasonography, Interventional / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Prevalence of asymptomatic carotid stenosis in patients undergoing infrainguinal bypass surgery.
Next Document:  Axillary lymphadenectomy for breast cancer without axillary drainage.