Document Detail

Ultrasonic myocardial texture versus Doppler analysis in hypertensive heart: a preliminary study.
MedLine Citation:
PMID:  9931083     Owner:  NLM     Status:  MEDLINE    
-Doppler-derived parameters of transmitral flow are useful indices of diastolic dysfunction in the hypertensive heart. Different degrees of myocardial involvement in hypertensive heart can be detected by videodensitometric myocardial textural analysis. The aim of this study was to compare Doppler-derived and ultrasonic videodensitometric parameters in the differentiation of healthy hearts from hypertensive hearts. We compared a group of age-matched (59+/-9 years) male essential hypertensive patients (n=53) with normotensive healthy subjects as controls (n=32). All subjects provided ambulatory blood pressure measurements for the evaluation of 24-hour mean systolic and diastolic blood pressure. A transmitral flow Doppler analysis was performed on all subjects. A quantitative analysis of the echocardiographic digitized imaging was performed with the help of a calibrated digitization system to calculate the septum and the posterior wall textural parameters. The myocardial mean gray level (MGL) was calculated to derive the cyclic variation index (CVI): (MGLend-diastolic-MGLend-systolic)/MGLend-diastolic x100. When compared with controls, the hypertensive patients showed a significantly lower CVI for both septum (-11.1+/-26.8% versus 34. 7+/-16.3%; P<0.001) and posterior wall (-11.2+/-27.6% versus 38. 2+/-15.4%; P<0.001). Individual analyses for the ratio of peak transmitral flow velocity in early diastole to the peak transmitral flow velocity in late diastole showed that only 24% of the patients (13/53) were discriminated from normal subjects by this parameter. Individual analyses for CVI, however, at both septum and posterior wall levels, showed that 74% of the patients (39/53) were discriminated from normal subjects by this second parameter. In comparison with Doppler-derived indices of diastolic filling, the videodensitometric parameters showed a significantly higher ability to discriminate between hypertensive subjects and normal controls.
V Di Bello; R Pedrinelli; D Giorgi; A Bertini; M Bianchi; M Paterni; M F Romano; G Dell'Omo; C Giusti
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Hypertension     Volume:  33     ISSN:  0194-911X     ISO Abbreviation:  Hypertension     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-02-19     Completed Date:  1999-02-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  66-73     Citation Subset:  IM    
Dipartimento di Medicina Interna, University of Pisa, Italy.
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MeSH Terms
Blood Pressure Monitoring, Ambulatory
Data Interpretation, Statistical
Echocardiography, Doppler*
Hypertension / physiopathology,  ultrasonography*
Hypertrophy, Left Ventricular / physiopathology,  ultrasonography*
Image Processing, Computer-Assisted*
Middle Aged
Ventricular Function, Left
Video Recording

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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