Document Detail


Ultrasonic characterization of myocardial photocoagulation lesion size in vivo during Nd:YAG laser irradiation.
MedLine Citation:
PMID:  8006180     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Endocardial coagulation lesions were created using transcatheter continuous-wave Nd:YAG laser irradiation. Ultrasound monitoring of thermal lesion dimensions was performed using 7.5-MHz and 10-MHz transducers directly from the epicardial surface in short-axis configuration (group A) or through the chest wall (group B). A total of 33 lesions were created in 10 dogs at energy levels ranging from 300 J to 1000 J. Mean histological lesion width (HW) compared with ultrasonically determined mean width (UW) showed that the differences (mean +/- standard deviation) in group A (UW - HW) was = 1.14 +/- 0.8 mm, which was not statistically significantly different from zero. In group B, (UW - HW) = 2.04 mm +/- 0.7 mm (p < .05), which was statistically significantly different from zero. Mean histological depth (HD) differentially related to ultrasound mean depth (UD) for group A and B combined showed (UD - HD) = -0.19 mm +/- 0.46 mm, not statistically significantly different from zero. The frequency distribution for width in group A showed magnitude of UW-HW > 3 mm in 32% of cases. In group B magnitude of UW-HW > 3 mm in 15%, whereas ultrasound width was larger than histology in 75% of the cases. For depth, magnitude of UD-HD > 3 mm in 15% of cases. With further refinement of the technique, ultrasonic tissue characterization may become a useful adjunct to monitoring lesion dimensions during transcatheter laser photocoagulation.
Authors:
R Splinter; J R Tuntelder; C H Chuang; M Thompson; L Littmann; R H Svenson; K R Dezern; G P Tatsis
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  22     ISSN:  0091-2751     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-07-21     Completed Date:  1994-07-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  221-9     Citation Subset:  IM    
Affiliation:
Laser and Applied Technologies Laboratory, Carolinas Medical Center, Charlotte, North Carolina 28203.
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MeSH Terms
Descriptor/Qualifier:
Animals
Body Temperature
Cardiomyopathies / etiology*,  pathology,  ultrasonography*
Dogs
Echocardiography*
Feasibility Studies
Female
Heart / radiation effects
Heart Catheterization
Laser Coagulation / adverse effects*
Male
Monitoring, Physiologic
Myocardium / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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