Document Detail


Ultrasensitive p24 antigen assay for diagnosis of perinatal human immunodeficiency virus type 1 infection.
MedLine Citation:
PMID:  17475763     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated an ultrasensitive p24 antigen enzyme immunosorbent assay on 802 plasma specimens from 582 infants and children of 0 to 180 days of age. Overall sensitivity and specificity were 91.7% and 98.5%, respectively. After exclusion of infants of less than 7 days of age, the sensitivity and specificity were 93.7% and 98.3%, respectively.
Authors:
Susan A Fiscus; Jeffrey Wiener; Elaine J Abrams; Marc Bulterys; Ada Cachafeiro; Richard A Respess
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.     Date:  2007-05-02
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  45     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-07-06     Completed Date:  2007-08-22     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2274-7     Citation Subset:  IM    
Affiliation:
University of North Carolina at Chapel Hill, Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA. fiscussa@med.unc.edu
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MeSH Terms
Descriptor/Qualifier:
Enzyme-Linked Immunosorbent Assay / methods*
HIV Core Protein p24 / analysis*,  blood*
HIV Infections / diagnosis*,  epidemiology
HIV-1
Humans
Infant
Infant, Newborn
Infant, Newborn, Diseases / diagnosis*,  epidemiology
Sensitivity and Specificity
United States
Grant Support
ID/Acronym/Agency:
P30 AI50410/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/HIV Core Protein p24
Comments/Corrections

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