| Ultrasensitive Quantitation of Human Immunodeficiency Virus Type 1 RNA in Plasma by the AMPLICOR and COBAS AMPLICOR HIV-1 MONITOR™ Tests. | |
| | |
MedLine Citation:
|
PMID: 21370156 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
The measurement of plasma human immunodeficiency virus type 1 (HIV-1) RNA levels has become an important tool for identifying individuals likely to benefit from antiretroviral therapy (1-7) as well as monitoring patients on therapy (8-14), and is now regarded as standard medical practice for managing the treatment of HIV-1-infected individuals (15-21). Three commercially available assays for measuring HIV-1 RNA levels are available. The firstgeneration AMPLICOR HIV-1 MONITOR™ Test, which uses reverse transcriptase-polymerase chain reaction (RT-PCR) technology, has a lower limit of quantitation of 400 copies/mL of plasma (22,23). The NucliSens HIV-1 QT Test (Organon Teknika, Boxtel, Netherlands), a second-generation assay based on the nucleic acid sequence-based amplification technique, has a lower limit of quantitation of 100 HIV-1 RNA copies/mL of plasma (24). The Quantiplex HIV-1 Version 2.0 Test (Chiron, Emeryville, CA), which uses the branched-chain DNA signal amplification technique, has a lower limit of quantitation of 500 HIV-1 RNA copies/mL of plasma (25,26). |
| | |
Authors:
|
S Herman; J Novotny; M Rosenstraus |
Related Documents
:
|
1898886 - Alterations in luteal phase progesterone and estradiol production after leuprolide acet... 16486466 - Critical point in complex plasmas. 6106576 - Trh-induced hyperprolactinemia and pituitary-ovarian function. 832726 - Plasma progesterone in women with a history of recurrent early abortions. 12130796 - Annual changes of urinary progesterone and estradiol-17beta of the dugong (dugong dugon... 12452316 - Plasma hepatocyte growth factor and the relationship between risk factors and carotid a... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Methods in molecular medicine Volume: 49 ISSN: 1543-1894 ISO Abbreviation: Methods Mol. Med. Publication Date: 2001 |
Date Detail:
|
Created Date: 2011-03-03 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101123138 Medline TA: Methods Mol Med Country: United States |
Other Details:
|
Languages: eng Pagination: 389-412 Citation Subset: - |
Affiliation:
|
Roche Molecular Systems, Alameda, CA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Detection and speciation of mycobacteria in formalin-fixed, paraffin-embedded tissue sections.
Next Document: Molecular diagnosis of hereditary thrombotic disorders.