Document Detail

Ulcerative necrobiosis lipoidica successfully treated with photodynamic therapy: Case report and literature review.
MedLine Citation:
PMID:  25150669     Owner:  NLM     Status:  Publisher    
Ulcerative Necrobiosis lipoidica (NL) is a rare skin condition refractory to conventional therapies. We treated a forty-four year old woman affected by widespread ulcerative NL with 6 sessions of topical ALA-PDT at two weeks intervals. At the end of the treatment a dramatic improvement of the clinical features was observed, with complete healing of cutaneous ulcers and marked reduction of erythema in all the treated areas. The mechanism of action of PDT in ulcer healing is still unknown; however, it is possible to hypothesize a combination of anti-inflammatory effect, immunomodulatory activity and keratinocytes photoactivation.
Francesco Borgia; Mario Vaccaro; Laura G Cantavenera; Emanuela Aragona; Serafinella P Cannavò
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-20
Journal Detail:
Title:  Photodiagnosis and photodynamic therapy     Volume:  -     ISSN:  1873-1597     ISO Abbreviation:  Photodiagnosis Photodyn Ther     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101226123     Medline TA:  Photodiagnosis Photodyn Ther     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier B.V.
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