Document Detail


UVA1 phototherapy for cutaneous diseases: an experience of 92 cases in the United States.
MedLine Citation:
PMID:  16948826     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The efficacy and safety of UVA1 (340-400 nm) phototherapy were established by studies from European countries. PURPOSE: Evaluate experience with UVA1 phototherapy for patients with cutaneous diseases in the United States. METHODS: A retrospective analysis of 92 cases of UVA1-treated cutaneous conditions from four medical centers in the United States was performed. RESULTS: Two-third of the patients showed a fair to good response (26-100% improvement) and one-third of the patients showed a poor response (0-25% improvement). Diseases with a moderate to good response (51-100% improvement) included scleredema adultorum, hand or foot dermatitis, atopic dermatitis, morphea (medium or medium- to high-dose UVA1), systemic sclerosis, and urticaria pigmentosa. Besides tanning, other adverse effects were found in 15% of patients, which include pruritus, erythema, tenderness, and burning sensation. Patients with skin types I-III responded better that those with a darker skin type. CONCLUSION: UVA1 phototherapy is a useful and well-tolerated treatment option for a variety of skin conditions.
Authors:
Chanisada Tuchinda; Holly A Kerr; Charles R Taylor; Heidi Jacobe; Bettany M Bergamo; Craig Elmets; Jennifer Rivard; Henry W Lim
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Photodermatology, photoimmunology & photomedicine     Volume:  22     ISSN:  0905-4383     ISO Abbreviation:  Photodermatol Photoimmunol Photomed     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-04     Completed Date:  2007-01-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013641     Medline TA:  Photodermatol Photoimmunol Photomed     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  247-53     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Henry Ford Hospital, Detroit, MI 48202, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Child, Preschool
Dermatitis, Atopic / epidemiology,  etiology,  pathology,  radiotherapy
Female
Foot Dermatoses / epidemiology,  etiology,  pathology,  radiotherapy
Hand Dermatoses / epidemiology,  etiology,  pathology,  radiotherapy
Humans
Male
Medical Records
Middle Aged
Retrospective Studies
Scleredema Adultorum / epidemiology,  etiology,  pathology,  radiotherapy
Severity of Illness Index
Skin Diseases / epidemiology*,  etiology,  pathology,  radiotherapy*
Treatment Outcome
Ultraviolet Therapy / adverse effects,  utilization*
United States / epidemiology
Urticaria Pigmentosa / epidemiology,  etiology,  pathology,  radiotherapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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