Document Detail


UV-inducible DNA repair in the cyanobacteria Anabaena spp.
MedLine Citation:
PMID:  3114232     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Strains of the filamentous cyanobacteria Anabaena spp. were capable of very efficient photoreactivation of UV irradiation-induced damage to DNA. Cells were resistant to several hundred joules of UV irradiation per square meter under conditions that allowed photoreactivation, and they also photoreactivated UV-damaged cyanophage efficiently. Reactivation of UV-irradiated cyanophage (Weigle reactivation) also occurred; UV irradiation of host cells greatly enhanced the plaque-forming ability of irradiated phage under nonphotoreactivating conditions. Postirradiation incubation of the host cells under conditions that allowed photoreactivation abolished the ability of the cells to perform Weigle reactivation of cyanophage N-1. Mitomycin C also induced Weigle reactivation of cyanophage N-1, but nalidixic acid did not. The inducible repair system (defined as the ability to perform Weigle reactivation of cyanophages) was relatively slow and inefficient compared with photoreactivation.
Authors:
E Levine; T Thiel
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of bacteriology     Volume:  169     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1987-10-07     Completed Date:  1987-10-07     Revised Date:  2010-09-10    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  3988-93     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cyanobacteria / drug effects,  genetics*,  radiation effects
DNA Repair / drug effects,  radiation effects*
Mitomycin
Mitomycins / pharmacology
Nalidixic Acid / pharmacology
Ultraviolet Rays*
Viruses / genetics,  radiation effects
Chemical
Reg. No./Substance:
0/Mitomycins; 389-08-2/Nalidixic Acid; 50-07-7/Mitomycin
Comments/Corrections

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