| UNK cells: their role in tissue re-modelling and preeclampsia. | |
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MedLine Citation:
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PMID: 17621698 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In different species of mammal, uterine natural killer (uNK) cells are massively recruited and presented at the fetal maternal interface with a spatio-temporal pattern, and regarded as a constructive element to support reproductive development. Recent insights highlight the uNK cells activation, function and interaction with local compartments, which all contribute to the initiation of vascular structural changes. New trends of uNK cells research will benefit the diagnosis, management and test treatment strategy of preeclampsia. Furthermore, we suggest that more efforts and specific studies are needed to further explore the role of uNK cells at the unique micro-environment. |
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Authors:
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Jianhong Zhang; Zhigang Tian |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Seminars in immunopathology Volume: 29 ISSN: 1863-2297 ISO Abbreviation: - Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-07-11 Completed Date: 2007-07-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101308769 Medline TA: Semin Immunopathol Country: Germany |
Other Details:
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Languages: eng Pagination: 123-33 Citation Subset: IM |
Affiliation:
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Institute of Immunology, Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, 230027 Hefei, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cytotoxicity, Immunologic Decidua / immunology, metabolism Embryo Implantation Female HLA Antigens / immunology, metabolism Humans Killer Cells, Natural / immunology* Lymphocyte Activation Lymphokines / immunology*, metabolism Maternal-Fetal Exchange / immunology* Pre-Eclampsia / immunology* Pregnancy Uterus / immunology* |
| Chemical | |
Reg. No./Substance:
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0/HLA Antigens; 0/Lymphokines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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