Document Detail

Tyrosine-rich crystalloids in neoplasms and tissues of the head and neck.
MedLine Citation:
PMID:  3755326     Owner:  NLM     Status:  MEDLINE    
Tyrosine-rich crystalloids were identified in three benign mixed tumors of the parotid gland, one terminal duct adenocarcinoma of a minor salivary gland, and the fibrous connective tissue of two laryngectomy specimens. Light and electron microscopic studies showed the crystalloids to be composed of irregular deposits of amorphous electron-dense material. In the salivary gland tumors this material was commonly associated with interstitial collagen and was found in greatest abundance near myoepithelial cells. This proximity suggests that the tyrosine-rich crystalloids result from the precipitation on stromal collagen of products secreted by neoplastic myoepithelial cells.
B R Harris; F Shipkey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  110     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1986-08-15     Completed Date:  1986-08-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  709-12     Citation Subset:  AIM; IM    
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MeSH Terms
Adenocarcinoma / analysis*,  ultrastructure
Head and Neck Neoplasms / analysis*,  ultrastructure
Laryngeal Neoplasms / analysis,  ultrastructure
Microscopy, Electron
Middle Aged
Parotid Neoplasms / analysis,  ultrastructure
Salivary Gland Neoplasms / analysis,  ultrastructure
Tyrosine / analysis*
Reg. No./Substance:

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