Document Detail

Tyramine-immunoreactive neuronal structures in the rat brain: abundance in the median eminence of the mediobasal hypothalamus.
MedLine Citation:
PMID:  15955414     Owner:  NLM     Status:  MEDLINE    
Immunoreactivity to p-tyramine, one of the natural trace amines, was studied in the rat brain by an anti-p-tyramine antibody. Immunoreactivity to this amine is very weak in the nigrostriatal dopaminergic neurons and terminals, and weak in the locus coeruleus noradrenergic ones. It was intensified in these structures after monoamine oxidase inhibition. On the other hand, this amine was highly concentrated in the median eminence of the mediobasal hypothalamus, in which its physiological function on prolactin release has been demonstrated.
K Kitahama; S Araneda; M Geffard; H Sei; H Okamura
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-04-26
Journal Detail:
Title:  Neuroscience letters     Volume:  383     ISSN:  0304-3940     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-06-15     Completed Date:  2005-08-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  215-9     Citation Subset:  IM    
CNRS UMR5123, Laboratoire de Physiologie Intégrative Cellulaire et Moléculaire, Université Claude Bernard, Villeurbanne, France.
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MeSH Terms
Aromatic-L-Amino-Acid Decarboxylases / metabolism
Dopamine / metabolism
Immunohistochemistry / methods
Median Eminence / drug effects,  metabolism*
Monoamine Oxidase Inhibitors / pharmacology
Substantia Nigra / metabolism
Tyramine / metabolism*
Reg. No./Substance:
0/Monoamine Oxidase Inhibitors; 51-67-2/Tyramine; EC Decarboxylases

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