| Typically atypical: histiocytoid Sweet syndrome, associated with malignancy. | |
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MedLine Citation:
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PMID: 21884413 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Sweet syndrome (acute febrile neutrophilic dermatosis) is characterized by a dramatic onset of high fever, neutrophilia and typical skin lesions. About 20 % of patients have an associated malignancy, most commonly hematologic diseases. Chronic and paucisymptomatic manifestations of Sweet syndrome may be misdiagnosed or misinterpreted as harmless, resulting in delayed diagnosis. "Atypical" manifestations are especially suspicious for associated malignancies. This is demonstrated by a 39-year old patient with chronic and afebrile disease who was referred to our clinic only after symptoms had persisted for several months. By that point, an underlying nodular lymphocyte predominant Hodgkin's lymphoma had already reached an advanced stage. Skin biopsies revealed dermal infiltrates of histiocytoid cells of myelogenous origin, supporting a diagnosis of histiocytoid Sweet syndrome. Specific cutaneous infiltrates associated with myelogenous leukemia were ruled out. |
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Authors:
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Anika Hünermund; Ana-Maria Wendel; Eva Geissinger; Eva-Bettina Bröcker; Johanna Stoevesandt |
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Publication Detail:
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Type: Journal Article Date: 2011-03-29 |
Journal Detail:
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Title: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG Volume: 9 ISSN: 1610-0387 ISO Abbreviation: J Dtsch Dermatol Ges Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-09-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101164708 Medline TA: J Dtsch Dermatol Ges Country: Germany |
Other Details:
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Languages: eng Pagination: 666-9 Citation Subset: IM |
Copyright Information:
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© The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin. |
Affiliation:
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Department of Dermatology, Venerology and Allergology, University of Würzburg, Germany Institute for Pathology, University of Würzburg, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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