Document Detail

Typhoid spondylodiscitis: the first reported case in Southeast Asia and review of the literature.
MedLine Citation:
PMID:  20196424     Owner:  NLM     Status:  MEDLINE    
We describe the first case of typhoid spondylodiscitis in Southeast Asia, and the literature were also reviewed. A 57-year-old diabetic Thai man who presented with a one-month course of progressive low back pain associated with paraparesis and bowel-bladder dysfunction. Examination revealed local tenderness over T12 area, spastic paraparesis, impaired pinprick sensation up to T12 level, and loose anal sphincter tone. Magnetic resonance imaging showed spondylodiscitis of T11 and T12 and epidural abscess causing spinal cord compression. T11 and T12 laminectomy, T11/12 discectomy, and debridement of epidural abscess were performed, and the cultures of the pus grew Salmonella Typhi. He was treated with intravenous ciprofloxacin for three weeks and was discharged from the hospital with oral ciprofloxacin and trimethoprim-sulfamethoxazole for another five months of treatment. The patient was doing well when last seen two months after discontinuation of antimicrobial treatment. In addition, a total of ten cases of typhoid spondylitis/spondylodiscitis were reviewed.
Gompol Suwanpimolkul; Sumanee Nilgate; Chusana Suankratay
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  93     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-03-03     Completed Date:  2010-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  137-41     Citation Subset:  IM    
Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
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MeSH Terms
Anti-Infective Agents / therapeutic use
Ciprofloxacin / therapeutic use
Diagnosis, Differential
Discitis / diagnosis*,  drug therapy,  microbiology*
Drug Therapy, Combination
Magnetic Resonance Imaging
Middle Aged
Trimethoprim-Sulfamethoxazole Combination / therapeutic use
Typhoid Fever / diagnosis*,  drug therapy
Reg. No./Substance:
0/Anti-Infective Agents; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination; 85721-33-1/Ciprofloxacin

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