Document Detail

Typhoid rhabdomyolysis with acute renal failure and acute pancreatitis: a case report and review of the literature.
MedLine Citation:
PMID:  19147385     Owner:  NLM     Status:  MEDLINE    
We report a case of typhoid rhabdomyolysis with acute renal failure and acute pancreatitis in a 23-year-old Vietnamese male who was admitted to the intensive care unit with a 15-day history of fever followed by severe abdominal pain. On examination, the patient was febrile and his abdomen was diffusely tender. Serum creatinine was 533 micromol/L, pancreatic amylase 1800 U/L and lipase 900 U/L; the myoglobin blood level was high, which is associated with significant myoglobinuria. Blood, urine and stool culture yielded Salmonella enterica serovar typhi, which was sensitive to ceftriaxon, ampicillin and ciprofloxacin. Ceftriaxon was initiated for a total of 14 days. Subsequently, the patient maintained a good urine output with improved renal parameters and accordingly was discharged. In this report, we review the literature and discuss the pathogenesis of the disease thoroughly.
Fahmi Yousef Khan; Ahmed Al-Ani; Hamda Abdulla Ali
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-01-14
Journal Detail:
Title:  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases     Volume:  13     ISSN:  1878-3511     ISO Abbreviation:  Int. J. Infect. Dis.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-28     Completed Date:  2009-11-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610933     Medline TA:  Int J Infect Dis     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  e282-5     Citation Subset:  IM    
Department of Medicine, Hamad General Hospital, Doha-Qatar.
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MeSH Terms
Acute Disease
Anti-Bacterial Agents / therapeutic use
Ceftriaxone / therapeutic use
Kidney Failure, Acute / diagnosis,  drug therapy,  etiology*
Pancreatitis / diagnosis,  drug therapy,  etiology*
Rhabdomyolysis / diagnosis,  drug therapy,  etiology*,  microbiology
Salmonella typhi / isolation & purification*
Typhoid Fever / complications*,  drug therapy,  microbiology
Young Adult
Reg. No./Substance:
0/Anti-Bacterial Agents; 73384-59-5/Ceftriaxone

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