Document Detail

Types of collagen in breast capsules.
MedLine Citation:
PMID:  2690718     Owner:  NLM     Status:  MEDLINE    
Representative sections of the capsules that envelop surgically implanted silicone were analyzed for their collagen content. The specimens were biopsied (as incidental procedures) as the opportunities arose. All four classes of capsules as codified clinically and those surrounding tissue expanders are represented. The ages of the capsules ranged from 6 weeks to 13 years. Eighteen specimens were examined by slab gel electrophoresis. Type I collagen predominated in all of the electrophoretic patterns. Type III collagen was consistently present in lesser concentrations. Type V collagen was consistently present as a small fraction. There was no evident correlation between the concentrations of the component collagens and the clinically assessed class of the capsules or of those from around tissue expanders, but there was a correlation to the age of the capsules. The electrophoretic patterns of the collagens of this study are indistinguishable from the (previously reported) analyses of (cutaneous) scar.
W R Marshall; M Godfrey; D W Hollister; M E Balkovich; V V Lindgren
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of plastic surgery     Volume:  23     ISSN:  0148-7043     ISO Abbreviation:  Ann Plast Surg     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1990-02-05     Completed Date:  1990-02-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7805336     Medline TA:  Ann Plast Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  401-5     Citation Subset:  IM    
Department of Surgery, Oregon Health Sciences University, Portland.
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MeSH Terms
Collagen / analysis*
Foreign-Body Reaction*
Middle Aged
Prostheses and Implants*
Reg. No./Substance:
0/Silicones; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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