Document Detail


Types of HLA in the bladder transitional cell carcinoma (TCC).
MedLine Citation:
PMID:  23348175     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
HLA plays a complementary role in the interaction between tumor and body immunology. The aim of this study was to determine the existence of the association between the HLA system and transitional cell carcinoma (TCC). Using standard micro-lymphocytotoxic method of Terasaki, HLA-A, B, DR and DQ antigen types of 30 patients with TCC of the bladder were compared with the control group (30 healthy people). In the TCC patient group, HLA -DQ6(1) and HLA -DQ7(3) antigens were detected with a signiicantly higher frequency than in the control group (p=0.018 and p=0.038, respectively), whereas HLA-A10, B4, DR53 and DQ1 antigens were detected with signiicantly higher frequency in the control group (p less 0.05 in all). It suggests that patients who had the antigens detected were at higher risk of TCC, and the ones who had the antigens displaying protective features as were detected in the control group, were at lesser risk.
Authors:
Erkan Yılmaz; Ali Uğur Özalp; Arman Cekmen; Bülent Eren; Bülent Onal; Emre Akkuş; Ergun Erdoğan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina     Volume:  10     ISSN:  1840-0132     ISO Abbreviation:  Med Glas Ljek komore Zenicko-doboj kantona     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101250177     Medline TA:  Med Glas Ljek komore Zenicko-doboj kantona     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  133-6     Citation Subset:  IM    
Affiliation:
1Blood Bank, Tissue Typing Laboratory, 2Urology Department; School of Medicine, Istanbul University, Cerrahpaşa, 3Bursa Morgue Department, Council of Forensic Medicine of Turkey, 3Bursa Morgue Department, Council of Forensic Medicine of Tur- key, Bursa, 4Pediatric Surgery Department, Cerrahpasa School of Medicine, Istanbul University; Turkey.
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