| Type I toxin-antitoxin systems in Bacillus subtilis. | |
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MedLine Citation:
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PMID: 23059907 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Type I toxin-antitoxin (TA) systems are widespread in bacteria and consist of a toxin-encoding mRNA and a partially overlapping antisense RNA that blocks expression of the toxin, either at the level of translation or by mRNA degradation. Four type I toxin families have so far been proposed in B. subtilis based on sequence similarity: TxpA/BsrG, BsrH/BsrE, YonT and YhzE and two (TxpA and BsrG) have been studied in some detail. Here we review what is known about these confirmed and putative toxin-antitoxin families in B. subtilis, their regulatory mechanisms, their potential roles and how they may link to the physiology of the cell. |
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Authors:
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Sylvain Durand; Natalie Jahn; Ciarán Condon; Sabine Brantl |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-11 |
Journal Detail:
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Title: RNA biology Volume: 9 ISSN: 1555-8584 ISO Abbreviation: RNA Biol Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101235328 Medline TA: RNA Biol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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CNRS UPR 9073 (affiliated with Univ. Paris Diderot, Sorbonne Paris Cité); Institut de Biologie Physico-Chimique; Paris, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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