Document Detail


Type A botulinum toxin: a new treatment for axillary and palmar hyperhidrosis.
MedLine Citation:
PMID:  12847738     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hyperhidrosis is an invalidating condition, and one that is difficult to treat. It is characterized by an excessive and uncontrolled production of sweat by the sweat glands, often causing psychological, social, and occupational problems for the patient. Hyperhidrosis can be distinguished in two forms: idiopathic (of unknown etiology), or secondary, due to an alteration of the endocrine system (ex: hyperthyroidism, neuropathy, neoplasia etc.) It is found in about 0.3-0.5% of the population and can be localized (axillary, palmar, plantar, facial) or diffused. The subcutaneous injection of type A botulinum toxin, until now used only for the treatment of blepharospasm or hemifacial spasm, has shown to be a useful treatment for localized hyperhidrosis. The objective of the authors is to evaluate the therapeutic efficacy, safety, and management of botulinum toxin treatment in patients affected with axillary or palmar hyperhidrosis resistant to conventional therapies.
Authors:
Luigi Rusciani; Enzo Severino; Antonio Rusciani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  1     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2003-07-09     Completed Date:  2003-07-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  147-51     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Catholic University of Sacred Heart, Largo A. Gemelli 8, 00168 Rome, Italy. itskcanf@rm.unicatt.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Botulinum Toxin Type A / adverse effects,  pharmacokinetics,  therapeutic use*
Female
Humans
Hyperhidrosis / classification,  drug therapy*
Male
Chemical
Reg. No./Substance:
0/Botulinum Toxin Type A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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