Document Detail


Type III units in the gerbil dorsal cochlear nucleus may be spectral notch detectors.
MedLine Citation:
PMID:  11764319     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Broadband sounds originating in the median plane are thought to be localized by neural processing of spectral notches introduced by the filtering action of the pinnae. Previous studies (Nelken, I., and E. D. Young. J. Neurophysiol. 71:2446-2462, 1994: Spirou, G. A., and E. D. Young. ibid. 66: 1750-1768. 1991) suggested that type IV units in decerebrate cat dorsal cochlear nucleus (DCN) are functional detectors of these spectral notches. Intracellular marking studies by Ding et al. (Ding, J., T. E. Benson, and H. F. Voigt. J. Neurophysiol. 82:3434-3457, 1999) have shown that type III units in gerbil arise from the DCN's principal output neurons, which are thought to have type IV unit properties in cat. A relative paucity of type IV units in the decerebrate gerbil (Davis. K. A., J. Ding, T. E. Benson, and H. F. Voigt. J. Neurophysiol. 75: 1411-1431, 1996) has motivated this study of spectral notch sensitivity in the gerbil DCN. Responses to notch noise stimuli were recorded from 15 gerbil type III units to investigate whether these units may function as spectral notch detectors. For narrow notch noise stimuli, all 15 units showed excitatory responses. For progressively wider notches, the discharge rate of 13/15 units became inhibited. As the maximum limits of notch width were approached, 11/15 units showed some degree of recovery from this inhibition. This response pattern in gerbil type III units possesses the salient features of notch noise responses in cat type IV units and implicates type III units in gerbilline spectral notch detection processes.
Authors:
J E Parsons; E Lim; H F Voigt
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  29     ISSN:  0090-6964     ISO Abbreviation:  Ann Biomed Eng     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-12-14     Completed Date:  2002-05-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  887-96     Citation Subset:  IM    
Affiliation:
Department of Biomedical Engineering, Hearing Research Center, Boston University, MA 02215-2407, USA.
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation / methods
Action Potentials / physiology
Animals
Cochlear Nucleus / physiology*
Electrophysiology
Gerbillinae
Interneurons / physiology*
Microelectrodes
Models, Neurological
Pitch Perception / physiology*
Sound Localization / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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