Document Detail


Type I CD36 deficiency associated with metabolic syndrome and vasospastic angina: a case report.
MedLine Citation:
PMID:  16886497     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 54-year-old man was admitted to our hospital for evaluation of chest pain occurring at rest in the morning. ST segment depression was observed during a treadmill exercise test. Coronary angiography identified spontaneous spasm of the proximal right coronary artery, and right coronary obstruction was improved from 90% to about 50% stenosis after intracoronary administration of nitroglycerin. Myocardial iodine-123 beta-methyl-p-iodophenyl-pentadecanoic acid uptake was absent, but thallium-201 uptake during single photon emission computed tomography was normal, and neither platelet nor monocyte expression of the CD36 molecule was observed, indicating type I CD36 deficiency. High blood pressure, elevated plasma triglyceride and fasting plasma glucose levels, and low high-density lipoprotein values suggested metabolic syndrome. The final diagnosis was type I CD 36 deficiency associated with metabolic syndrome and vasospastic angina.
Authors:
Masataka Kamiya; Akihiro Nakagomi; Yukichi Tokita; Masahiro Yasutake; Yoshiki Kusama; Morimasa Takayama; Teruo Takano
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cardiology     Volume:  48     ISSN:  0914-5087     ISO Abbreviation:  J Cardiol     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-08-04     Completed Date:  2006-08-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  41-4     Citation Subset:  IM    
Affiliation:
First Department of Internal Medicine, Nippon Medical School, Sendagi 1-1-5, Bunkyo-ku, Tokyo 113-8603.
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MeSH Terms
Descriptor/Qualifier:
Angina Pectoris, Variant / immunology*,  physiopathology
Antigens, CD36 / metabolism*
Coronary Vasospasm / immunology*
Electrocardiography
Heart / radionuclide imaging
Humans
Iodine Radioisotopes / diagnostic use
Iodobenzenes / diagnostic use
Male
Metabolic Syndrome X / immunology*
Middle Aged
Tomography, Emission-Computed, Single-Photon
Chemical
Reg. No./Substance:
0/Antigens, CD36; 0/Iodine Radioisotopes; 0/Iodobenzenes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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