| Type B3 thymic epithelial tumor in an adolescent detected by immunohistochemical staining for CD5, CD99, and KIT (CD117): a case report. | |
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MedLine Citation:
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PMID: 19901887 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 16-year-old male patient was admitted to the hospital for a medical workup to examine an anterior mediastinal tumor in April 2000. A tumor excision and a right lower lung lobe nodule resection were performed in June 2000. The tumor tissue showed a cobblestone-like proliferation of atypical cells containing a discrete nucleolus that were aligned in an epithelial fashion against mainly lymphocytic inflammatory cells in the background; also shown were undifferentiated tumor cells with epithelioid characteristics. Immunohistochemical staining for CD5, CD99, and KIT (CD117) revealed that the tumor cells were CD5-negative and that some of the lymphocytes infiltrating the tumor tissue stained positive for CD99 and negative for KIT. The lesion was therefore diagnosed to be a type B3 thymic epithelial tumor. |
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Authors:
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Naoyuki Yoshino; Hirotoshi Kubokura; Shigeo Yamauchi; Yoshiharu Oaki; Kiyoshi Koizumi; Kazuo Shimizu |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia Volume: 15 ISSN: 2186-1005 ISO Abbreviation: Ann Thorac Cardiovasc Surg Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-11-10 Completed Date: 2010-01-14 Revised Date: 2012-06-18 |
Medline Journal Info:
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Nlm Unique ID: 9703158 Medline TA: Ann Thorac Cardiovasc Surg Country: Japan |
Other Details:
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Languages: eng Pagination: 324-7 Citation Subset: IM |
Affiliation:
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Department of Surgery, Division of Thoracic Surgery, Nippon Medical School, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Antigens, CD / analysis* Antigens, CD5 / analysis* Cell Adhesion Molecules / analysis* Humans Immunohistochemistry* Male Proto-Oncogene Proteins c-kit / analysis* Thymoma / immunology*, pathology, surgery Thymus Neoplasms / immunology*, pathology, surgery Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD; 0/Antigens, CD5; 0/CD99 protein, human; 0/Cell Adhesion Molecules; EC 2.7.10.1/Proto-Oncogene Proteins c-kit |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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