Document Detail


Type 1 diabetes mellitus and pregnancy.
MedLine Citation:
PMID:  21364860     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Diabetes complicates up to 10% of all pregnancies in the United States. Of these, 0.2% to 0.5% are patients with type 1 diabetes mellitus (T1DM). Pregnancies affected by T1DM are at increased risk for preterm delivery, preeclampsia, macrosomia, shoulder dystocia, intrauterine fetal demise, fetal growth restriction, cardiac and renal malformations, in addition to rare neural conditions such as sacral agenesis. Intensive glycemic control and preconception planning have been shown to decrease the rate of fetal demise and malformations seen in pregnancies complicated by T1DM. Recent advances in insulin formulations and delivery methods have increased the number of options available to the obstetric team. Insulin regimens should be tailored to each individual patient to maximize compliance and ensure proper glycemic control. Intensive preconception counseling with frequent follow-up visits emphasizing tight glucose control is recommended for adequate management.
Authors:
Roberto Vargas; John T Repke; Serdar H Ural
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reviews in obstetrics & gynecology     Volume:  3     ISSN:  2153-8166     ISO Abbreviation:  Rev Obstet Gynecol     Publication Date:  2010  
Date Detail:
Created Date:  2011-03-02     Completed Date:  2011-07-14     Revised Date:  2014-08-28    
Medline Journal Info:
Nlm Unique ID:  101479674     Medline TA:  Rev Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  92-100     Citation Subset:  -    
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