Document Detail


Two young adults who had acute coronary syndrome after regression of coronary aneurysms caused by Kawasaki disease in infancy.
MedLine Citation:
PMID:  16565902     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report two young adult patients who had acute coronary syndrome after regression of coronary aneurysms caused by Kawasaki disease (KD). A 26 year-old man had acute anterior myocardial infarction at midnight after drinking alcohol. He had had bilateral coronary aneurysms caused by KD at the age of 8 months. Selective coronary angiograms (CAGs) at the age of 7 years revealed regression of both coronary aneurysms. He had no symptoms until the onset of acute myocardial infarction. The other patient was a 24 year-old man diagnosed as having a subendocardial infarction. He had had bilateral coronary aneurysms caused by KD at the age of 1 year. CAGs at the age of 9 years showed that both had regressed. It should be recognized that young adults with apparently normal coronary arteries angiographically after regression of large coronary aneurysms caused by KD may occasionally have acute coronary syndromes. We suspect intimal involvement of the coronary arterial wall after regression of the large aneurysms underlies the acute coronary syndrome in adults. Risk factors for atherosclerosis must be avoided in this population.
Authors:
E Tsuda; A Hanatani; K Kurosaki; H Naito; S Echigo
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  27     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-05-29     Completed Date:  2006-10-31     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  372-5     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, Osaka, 565-8565, Japan. etsuda@hsp.ncvc.go.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Angina, Unstable / etiology*
Coronary Angiography
Coronary Vessels / pathology
Dilatation, Pathologic
Heart Aneurysm / complications,  etiology*,  radiography
Humans
Male
Mucocutaneous Lymph Node Syndrome / complications*
Myocardial Infarction / etiology*
Syndrome
Time Factors

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