| Two years' experience with an enhanced chemiluminescent assay for neonatal blood spot TSH. | |
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MedLine Citation:
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PMID: 9247672 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have developed a blood spot assay for thyroid stimulating hormone (TSH) based on the Amerlite TSH-30 serum assay for use in the Welsh neonatal hypothyroid screening programme. A total of 67,656 infants were screened in 1994 and 1995, and 28 cases of primary hypothyroidism were detected, giving a prevalence of one in 2416. The method is sensitive and rapid, results being available within 3 h of receipt of samples. The assay enables much faster detection of primary hypothyroidism than was previously possible, and therefore contributes to earlier treatment of affected infants. |
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Authors:
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R John; R Henley; N Oversby |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of clinical biochemistry Volume: 34 ( Pt 4) ISSN: 0004-5632 ISO Abbreviation: Ann. Clin. Biochem. Publication Date: 1997 Jul |
Date Detail:
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Created Date: 1997-09-15 Completed Date: 1997-09-15 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0324055 Medline TA: Ann Clin Biochem Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 396-9 Citation Subset: IM |
Affiliation:
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Department of Medical Biochemistry, University Hospital of Wales, Healthcare NHS Trust, Heath Park, Cardiff, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chemiluminescent Measurements Congenital Hypothyroidism Female Humans Hypothyroidism / diagnosis* Immunoenzyme Techniques* Infant, Newborn Male Mass Screening Quality Control Reagent Kits, Diagnostic Sensitivity and Specificity Thyrotropin / blood* Wales |
| Chemical | |
Reg. No./Substance:
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0/Reagent Kits, Diagnostic; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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