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Two-year survival and neurological outcome of in-hospital cardiac arrest patients rescued by extracorporeal cardiopulmonary resuscitation.
MedLine Citation:
PMID:  23664696     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: The clinical benefit of extracorporeal cardiopulmonary resuscitation (E-CPR) has been proved in short-term follow-up studies. However, the benefit of E-CPR beyond 1year has been not known. We investigated 2-year outcome of patients who received E-CPR or conventional CPR (C-CPR). METHODS: We analyzed a total of 406 adult in-hospital cardiac arrest victims who underwent CPR for more than 10min from 2003 to 2009. The two-year survival and neurological outcome of E-CPR (n=85) and C-CPR (n=321) were compared using propensity score-matched analysis. RESULTS: The 2-year survival with minimal neurological impairment was 4-fold higher in the E-CPR group than the C-CPR group (23.5% versus 5.9%, hazard ratio (HR)=0.57, 95% confidence interval (CI)=0.43-0.75, p<0.001) by unadjusted analysis. After propensity-score matching, it was still 4-fold higher in the E-CPR group than the C-CPR group (20.0% versus 5.0%, HR=0.53, 95% CI=0.36-0.80, p=0.002). In the E-CPR group, the independent predictors associated with minimal neurological impairment were age ≤65years (HR=0.46; 95% CI=0.26-0.81; p=0.008), CPR duration ≤35min (HR=0.37; 95% CI=0.18-0.76; p=0.007), and subsequent cardiovascular intervention including coronary intervention or cardiac surgery (HR=0.36; 95% CI=0.18-0.68; p=0.002). CONCLUSIONS: The initial survival benefit of E-CPR for cardiac arrest patients persisted at 2years.
Authors:
Tae Gun Shin; Ik Joon Jo; Min Seob Sim; Yong-Bien Song; Jung-Hoon Yang; Joo-Yong Hahn; Seung Hyuk Choi; Hyeon-Cheol Gwon; Eun-Seok Jeon; Kiick Sung; Young Tak Lee; Jin-Ho Choi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-5-9
Journal Detail:
Title:  International journal of cardiology     Volume:  -     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-5-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Emergency Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
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