Document Detail


Two-voxel localization sequence for in vivo two-dimensional homonuclear correlation spectroscopy.
MedLine Citation:
PMID:  11273760     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The combination of localized 2D 1H MR correlation spectroscopy and Hadamard encoding allows the simultaneous acquisition of multiple volumes of interest without an increase in the experimental duration, compared to single-voxel acquisition. In the present study, 2D correlation spectra were acquired simultaneously within 20 to 40 min in two voxels located in each hemisphere of the rat brain. An intervoxel distance of 20% of the voxel size was sufficient to limit spatial contamination. The following cerebral metabolites gave detectable crosspeaks: N-acetylaspartate, the glutamate/glutamine pool, aspartate, phosphoethanolamine, glucose, glutathione, taurine, myo-inositols, lactate, threonine, gamma-aminobutyric acid, and alanine. Most of the metabolites were measured without contamination of other resonances.
Authors:
F Delmas; J C Beloeil; B P van der Sanden; K Nicolay; B Gillet
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of magnetic resonance (San Diego, Calif. : 1997)     Volume:  149     ISSN:  1090-7807     ISO Abbreviation:  J. Magn. Reson.     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-29     Completed Date:  2001-07-26     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  9707935     Medline TA:  J Magn Reson     Country:  United States    
Other Details:
Languages:  eng     Pagination:  119-25     Citation Subset:  IM    
Copyright Information:
Copyright 2001 Academic Press.
Affiliation:
Laboratoire de RMN Biologique, ICSN-CNRS, Gif sur Yvette, 91198, France.
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / physiology
Brain Damage, Chronic / physiopathology*
Brain Ischemia / physiopathology*
Dominance, Cerebral / physiology*
Energy Metabolism / physiology*
Image Enhancement
Image Processing, Computer-Assisted*
Lactic Acid / metabolism
Magnetic Resonance Imaging*
Magnetic Resonance Spectroscopy*
Phantoms, Imaging
Rats
Reference Values
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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