Document Detail


Two successful vaginal births after cesarean section in a patient with Hermansky-Pudlak syndrome who was treated with 1-deamino-8-arginine-vasopression during labor.
MedLine Citation:
PMID:  19160629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe the obstetric management for a patient with Hermansky-Pudlak syndrome (HPS) and a previous cesarean delivery. The disease is characterized by oculocutaneous albinism, platelet storage dysfunction, and lipofuscin deposits in the reticuloendothelial system. Patients with the disorder are at high risk for major morbidity secondary to bleeding complications. The patient was a 22-year-old military spouse from Puerto Rico with HPS and a history of severe hemorrhage during cesarean delivery of her first child. In this report, we discuss the pathophysiologic features of HPS and the prophylactic administration of 1-deamino-8-arginine-vasopression during labor to minimize blood loss.
Authors:
Ronald D Beesley; Randal D Robinson; Theresa L Stewart
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Military medicine     Volume:  173     ISSN:  0026-4075     ISO Abbreviation:  Mil Med     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2009-01-23     Completed Date:  2009-02-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984771R     Medline TA:  Mil Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1048-9     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Vermont, Burlington, VT 05401, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Deamino Arginine Vasopressin / therapeutic use*
Female
Hemostatics / therapeutic use*
Hermanski-Pudlak Syndrome / physiopathology*
Humans
Postpartum Hemorrhage / drug therapy*
Pregnancy
Pregnancy Complications / prevention & control
Vaginal Birth after Cesarean*
Chemical
Reg. No./Substance:
0/Hemostatics; 16679-58-6/Deamino Arginine Vasopressin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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