Document Detail


Two sisters with Escobar syndrome.
MedLine Citation:
PMID:  7677145     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report on 2 sisters with an autosomal-recessive multiple pterygium syndrome, type Escobar, consisting of multiple pterygia with severe contractures, short stature, and minor facial and external genital anomalies. The striking finding was severe muscular atrophy. We speculate that a neuromuscular disorder is the underlying pathogenesis of Escobar syndrome.
Authors:
S Spranger; M Spranger; H M Meinck; G Tariverdian
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of medical genetics     Volume:  57     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-10-19     Completed Date:  1995-10-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  425-8     Citation Subset:  IM    
Affiliation:
Institute of Human Genetics and Anthropology, University of Heidelberg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / genetics,  physiopathology*
Arthrogryposis / physiopathology
Body Height
Child
Face / abnormalities
Female
Genitalia, Female / abnormalities
Hand Deformities, Congenital / physiopathology
Humans
Infant, Newborn
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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