Document Detail


Two proto-oncogenes that play dual roles in embryonal cell growth and differentiation.
MedLine Citation:
PMID:  8507557     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The function of growth factors in early development is reviewed. Special emphasis is on the epidermal growth factor and its receptor, and on the c-fos and its family of transcriptional factor proteins, which play an important role in modulating the growth and differentiation of early embryos and embryonal carcinoma cells.
Authors:
E D Adamson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of developmental biology     Volume:  37     ISSN:  0214-6282     ISO Abbreviation:  Int. J. Dev. Biol.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-07-09     Completed Date:  1993-07-09     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8917470     Medline TA:  Int J Dev Biol     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  111-6     Citation Subset:  IM    
Affiliation:
La Jolla Cancer Research Foundation, CA 92037.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blastocyst / chemistry*
Cell Differentiation
Embryonal Carcinoma Stem Cells
Epidermal Growth Factor / genetics,  physiology*
Genes, jun
Mice
Neoplastic Stem Cells / chemistry
Proto-Oncogene Proteins c-fos / analysis,  physiology*
Receptor, Epidermal Growth Factor / analysis,  physiology*
Signal Transduction
Teratoma / chemistry,  genetics,  metabolism*
Chemical
Reg. No./Substance:
0/Proto-Oncogene Proteins c-fos; 62229-50-9/Epidermal Growth Factor; EC 2.7.10.1/Receptor, Epidermal Growth Factor

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