Document Detail

Two pregnancy-associated late relapses in acute lymphoblastic leukemia.
MedLine Citation:
PMID:  2511099     Owner:  NLM     Status:  MEDLINE    
Late relapses of acute lymphoblastic leukemia occurred in two women in associated with pregnancy, 7 and 17 years, respectively, after the initial diagnosis of leukemia. In both cases and in a similar pregnancy-associated case in the literature relapse was accompanied by the appearance of vacuolization in the leukemic lymphoblasts. In order to explain how late relapses can occur at all and how they may be triggered by endocrine events such as pregnancy, it seems necessary to assume that some leukemic cells are not autonomous and that they may preserve the faculty of normal homeostatic regulation.
H Brincker; B E Christensen; S Cold
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Haematologica     Volume:  74     ISSN:  0390-6078     ISO Abbreviation:  Haematologica     Publication Date:    1989 May-Jun
Date Detail:
Created Date:  1990-01-09     Completed Date:  1990-01-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0417435     Medline TA:  Haematologica     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  289-91     Citation Subset:  IM    
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MeSH Terms
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / etiology*
Pregnancy Complications, Neoplastic*

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