Document Detail

Two populations of calbindin D28k-immunoreactive neurones in the striatum of the rat.
MedLine Citation:
PMID:  8100472     Owner:  NLM     Status:  MEDLINE    
In order to examine the localisation of calbindin D28k in the normal striatum of the rat, immunocytochemistry using monoclonal antibodies was carried out at both the light and electron microscopic levels. As has previously been shown, many striatal spiny neurones were immunopositive, however, a small population of neurones with smooth dendrites and indented nuclei were also identified. At least some of these cells also displayed NADPH-diaphorase activity. These findings indicate that, in common with the primate striatum and grafted striatal tissue in the rat, the normal rat striatum contains at least two populations of neurones that express calbindin D28k.
B D Bennett; J P Bolam
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain research     Volume:  610     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-08-03     Completed Date:  1993-08-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  305-10     Citation Subset:  IM    
MRC Anatomical Neuropharmacology Unit, Oxford, UK.
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MeSH Terms
Antibodies, Monoclonal / pharmacology
Basal Ganglia / cytology,  metabolism
Calcium-Binding Protein, Vitamin D-Dependent / immunology,  metabolism*
Corpus Striatum / cytology*,  immunology,  ultrastructure
Cross Reactions
NADPH Dehydrogenase / immunology,  metabolism
Neurons / immunology,  metabolism*
Neuropeptide Y / immunology,  metabolism
Rats, Wistar
Somatostatin / immunology,  metabolism
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Calcium-Binding Protein, Vitamin D-Dependent; 0/Neuropeptide Y; 0/calbindin; 51110-01-1/Somatostatin; EC Dehydrogenase

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