| Two pharmacy interventions to improve refill persistence for chronic disease medications: a randomized, controlled trial. | |
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MedLine Citation:
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PMID: 19106728 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Despite the proven effectiveness of many medications for chronic diseases, many patients do not refill their prescriptions in the required timeframe. OBJECTIVE: Compare the effectiveness of 3 pharmacist strategies to decrease time to refill of prescriptions for common chronic diseases. RESEARCH DESIGN/SUBJECTS: A randomized, controlled clinical trial with patients as the unit of randomization. Nine pharmacies within a medium-sized grocery store chain in South Carolina were included, representing urban, suburban, and rural areas and patients from a variety of socioeconomic backgrounds. Patients (n = 3048) overdue for refills for selected medications were randomized into 1 of 3 treatment arms: (1) pharmacist contact with the patient via telephone, (2) pharmacist contact with the patient's prescribing physician via facsimile, and (3) usual care. MEASURES: The primary outcome was the number of days from their recommended refill date until the patient filled a prescription for any medication relevant to his/her chronic disease. Prescription refill data were obtained routinely from the pharmacy district office's centralized database. Patient disposition codes were obtained by pharmacy employees. An intent-to-treat approach was used for all analyses. RESULTS: There were no significant differences by treatment arm in the study outcomes. CONCLUSIONS: Neither of the interventions is more effective than usual care at improving persistence of prescription refills for chronic diseases in overdue patients. |
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Authors:
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Paul J Nietert; Barbara C Tilley; Wenle Zhao; Peter F Edwards; Andrea M Wessell; Patrick D Mauldin; Pam P Polk |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Medical care Volume: 47 ISSN: 1537-1948 ISO Abbreviation: Med Care Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2008-12-24 Completed Date: 2009-01-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0230027 Medline TA: Med Care Country: United States |
Other Details:
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Languages: eng Pagination: 32-40 Citation Subset: IM |
Affiliation:
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Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA. nieterpj@musc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Chronic Disease / drug therapy*, ethnology Clinical Pharmacy Information Systems Directive Counseling / utilization Drug Utilization* Humans Insurance, Pharmaceutical Services Medicaid Medication Adherence / ethnology, statistics & numerical data* Middle Aged Outcome Assessment (Health Care) Pharmacies / organization & administration* Program Evaluation Proportional Hazards Models Reminder Systems / classification*, utilization Socioeconomic Factors South Carolina Telefacsimile / utilization* Telephone / utilization* Time Factors United States |
| Grant Support | |
ID/Acronym/Agency:
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P01 HS10871/HS/AHRQ HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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