Document Detail

Two new triterpenoids from Photinia serrulata.
MedLine Citation:
PMID:  18259146     Owner:  NLM     Status:  MEDLINE    
Two new triterpenoids, 2alpha,3beta,11alpha,13beta-tetrahydroxy-12-ketooleanan-28-oic acid(1) and 3beta-hydroxy-12-keto-9(11)-ursen-28,13beta-olide (2) were isolated from the leaves ofPhotinia serrulata. Their structures were identified by spectral methods. Compounds 1 and2 were assessed for cytotoxic activity against three human tumor cell lines (A-549, HCT-8,and BEL-7402), and they showed no cytotoxic effects at concentrations up to 5microg/mL.
Yaling Song; Yuehu Wang; Qing Lu; Jinming Gao; Minggang Bi; Yongxian Cheng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-12-20
Journal Detail:
Title:  Molecules (Basel, Switzerland)     Volume:  12     ISSN:  1420-3049     ISO Abbreviation:  Molecules     Publication Date:  2007  
Date Detail:
Created Date:  2008-02-08     Completed Date:  2008-04-07     Revised Date:  2009-10-27    
Medline Journal Info:
Nlm Unique ID:  100964009     Medline TA:  Molecules     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  2599-604     Citation Subset:  IM    
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.
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MeSH Terms
Cell Death / drug effects
Cell Line, Tumor
Magnetic Resonance Spectroscopy
Photinia / chemistry*
Triterpenes / chemistry,  isolation & purification*,  pharmacology
Reg. No./Substance:

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