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Two new saponins from Thalictrum fortunei.
MedLine Citation:
PMID:  22375870     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Two new cycloartane glycosides were isolated from the aerial parts of Thalictrum fortunei (Ranunculaceae). The chemical structures of these compounds were elucidated as 3-O-β-d-glucopyranosyl (1 → 4)-β-d-fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,30-tetraol 26-O-β-d-glucopyranoside and 3-O-β-d-glucopyranosyl (1 → 4)-β-d-fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,29-tetraol 26-O-β-d-glucopyranoside by extensive 1D and 2D NMR methods, HR-ESI-MS, and hydrolysis. Their cytotoxic activities toward human hepatoma Bel-7402 cells, human colon carcinoma LoVo cells, and human non-small-cell lung cancer NCIH-460 cells were evaluated by MTT assay, respectively.
Authors:
Xian-Tao Zhang; Shu-Wei Ma; Hao-Yan Jiao; Qing-Wen Zhang
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of Asian natural products research     Volume:  14     ISSN:  1477-2213     ISO Abbreviation:  J Asian Nat Prod Res     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888334     Medline TA:  J Asian Nat Prod Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  327-32     Citation Subset:  IM    
Affiliation:
a Guangdong Research Institute of Traditional Chinese Medicine , Guangzhou , 510520 , China.
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